Most of today’s common major diseases are metabolic in nature, meaning they have to do with how the body processes energy. Diabetes and heart disease top the list of metabolic diseases. In a new study published in Nutrition & Metabolism, researchers from Boston College have proposed that cancer is also fundamentally a metabolic disease. They argue that “essentially all hallmarks of cancer… can be linked to impaired mitochondrial function and energy metabolism.”
If this new hypothesis gains general acceptance, it could lead to major changes in how cancer is prevented and managed. Specifically, they suggest the cancer can be “starved”. They write, “Two major conclusions emerge from the hypothesis; first that many cancers can regress if energy intake is restricted and, second, that many cancers can be prevented if energy intake is restricted. Consequently, energy restricted diets combined with drugs targeting glucose and glutamine can provide a rational strategy for the longer-term management and prevention of most cancers.
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